Article

Identification of genetic and non-genetic modifiers of genomic imprinting through whole genome screening in humans

2025-04-01

Abstract excerpt

Genomic imprinting is required for normal development, and abnormal methylation of differentially methylated regions (iDMRs) controlling the parent of origin-dependent expression of the imprinted genes has been found in constitutional disorders affecting growth, metabolism, neurobehavior, and in cancer. In most of these cases the cause of the imprinting abnormalities is unknown. Also, these studies have generally...

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Literature Corpus work: 49b4413a-cf2d-597d-97d7-8215676bf100
DOI: 10.1101/2025.03.27.645693

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