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Article

TNF-α Promoter Polymorphisms Predict the Response to Etanercept More Powerfully than that to Infliximab/Adalimumab in Spondyloarthritis.

Scientific reports - 31 Aug 2016

Liu Jing, Dong Zheng, Zhu Qi, He Dongyi, Ma Yanyun, Du Aiping, He Fan, Zhao Dongbao, Xu Xia, Zhang Hui, Jin Li, Wang Jiucun

Abstract excerpt

While previous studies have researched in association analyses between TNFα promoter polymorphisms and responses to TNF blockers in spondyloarthritis patients, their results were conflicting. Therefore, we aimed to determine whether TNFα promoter polymorphisms could predict response to TNF blockers and find the source of heterogeneity. Data were extracted and analyzed from published articles and combined with our...

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Topics

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Share to Adalimumab
Share to Etanercept

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Infliximab

Share to Polymorphism, Genetic

Share to Predictive Value of Tests

Share to Promoter Regions, Genetic

Share to Spondylitis, Ankylosing

Share to Tumor Necrosis Factor-alpha

Source

Open in PubMed Open full text

Identifiers

PMID: 27578555
DOI: 10.1038/srep32202
PMCID: PMC5006048

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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