Article
Characterization of the sea urchin mitochondrial transcription factor A reveals unusual features.
Mitochondrion - 1 Jan 2014
Deceglie Stefania, Lionetti Claudia, Stewart James B, Habermann Bianca, Roberti Marina, Cantatore Palmiro, Loguercio Polosa Paola
Abstract excerpt
Sea urchin mtDNA is transcribed via a different mechanism compared to vertebrates. To gain information on the apparatus of sea urchin mitochondrial transcription we have characterized the DNA binding properties of the mitochondrial transcription factor A (TFAM). The protein contains two HMG box domains but, differently from vertebrates, displays a very short C-terminal tail. Phylogenetic analysis showed that the...
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