Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dimerization and Transactivation Domains as Candidates for Functional Modulation and Diversity of Sox9.

PloS one - 1 Jan 2016

Geraldo Marcos Tadeu, Valente Guilherme Targino, Nakajima Rafael Takahiro, Martins Cesar

Abstract excerpt

Sox9 plays an important role in a large variety of developmental pathways in vertebrates. It is composed of three domains: high-mobility group box (HMG box), dimerization (DIM) and transactivation (TAD). One of the main processes for regulation and variability of the pathways involving Sox9 is the self-gene expression regulation of Sox9. However, the subsequent roles of the Sox9 domains can also generate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Conserved Sequence
Share to Evolution, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Phylogeny

Share to Protein Domains

Share to Protein Multimerization

Share to SOX9 Transcription Factor

Source

Open in PubMed Open full text

Identifiers

PMID: 27196604
DOI: 10.1371/journal.pone.0156199
PMCID: PMC4873142

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dimerization and Transactivation Domains as Candidates for Functional Modulation and Diversity of Sox9.PMID 27196604Read ↗

Molecular evolution and inheritance pattern of Sox gene family among BovidaeSemantic proximity Read ↗

Diversification pattern of the HMG and SOX family members during evolution.Semantic proximity Read ↗

Distinct Transcriptional Programs Underlie Sox9 Regulation of the Mammalian ChondrocyteSemantic proximity Read ↗

Sox proteins: regulators of cell fate specification and differentiationSemantic proximity Read ↗

Amino acid function and docking site prediction through combining disease variants, structure alignments, sequence alignments, and molecular dynamics: a study of the HMG domain.Semantic proximity Read ↗

Sox genes find their feet.Semantic proximity Read ↗

Loss of DNA-dependent dimerization of the transcription factor SOX9 as a cause for campomelic dysplasia.Semantic proximity Read ↗

SOX E genes: SOX9 and SOX8 in mammalian testis developmentSemantic proximity Read ↗

Primate DAX1, SRY, and SOX9: evolutionary stratification of sex-determination pathway.Semantic proximity Read ↗

Evolution of the recombination regulator PRDM9 in minke whales.Semantic proximity Read ↗

Analysis of medaka sox9 orthologue reveals a conserved role in germ cell maintenance.Semantic proximity Read ↗

Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birdsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.