Article
SAF-Box, a conserved protein domain that specifically recognizes scaffold attachment region DNA.
Molecular and cellular biology - 1 Oct 2000
Kipp M, Göhring F, Ostendorp T, van Drunen C M, van Driel R, Przybylski M, Fackelmayer F O
Abstract excerpt
SARs (scaffold attachment regions) are candidate DNA elements for partitioning eukaryotic genomes into independent chromatin loops by attaching DNA to proteins of a nuclear scaffold or matrix. The interaction of SARs with the nuclear scaffold is evolutionarily conserved and appears to be due to specific DNA binding proteins that recognize SARs by a mechanism not yet understood. We describe a novel, evolutionarily...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
