Article
Cerebellar development in the absence of Gbx function in zebrafish.
Developmental biology - 1 Feb 2014
Su Chen-Ying, Kemp Hilary A, Moens Cecilia B
Abstract excerpt
The midbrain-hindbrain boundary (MHB) is a well-known organizing center during vertebrate brain development. The MHB forms at the expression boundary of Otx2 and Gbx2, mutually repressive homeodomain transcription factors expressed in the midbrain/forebrain and anterior hindbrain, respectively. The genetic hierarchy of gene expression at the MHB is complex, involving multiple positive and negative feedback loops...
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