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Article

Trajectories of memory decline in preclinical Alzheimer's disease: results from the Australian Imaging, Biomarkers and Lifestyle Flagship Study of ageing.

Neurobiology of aging - 1 Mar 2015

Pietrzak Robert H, Lim Yen Ying, Ames David, Harrington Karra, Restrepo Carolina, Martins Ralph N, Rembach Alan, Laws Simon M, Masters Colin L, Villemagne Victor L, Rowe Christopher C, Maruff Paul

Abstract excerpt

Memory changes in preclinical Alzheimer's disease (AD) are often characterized by heterogenous trajectories. However, data regarding the nature and determinants of predominant trajectories of memory changes in preclinical AD are lacking. We analyzed data from 333 cognitively healthy older adults who participated in a multicenter prospective cohort study with baseline and 18-, 36-, and 54-month follow-up...

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Identifiers

PMID: 25585532
DOI: 10.1016/j.neurobiolaging.2014.12.015

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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