Article
[Relationship between polymorphisms of tumor necrosis factor alpha gene and primary myelodysplastic syndromes].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Oct 2013
Xu Jun-qing, Wang Jie-yu, Qin Tie-jun, Xu Ze-feng, Fang Li-wei, Pan Li-juan, Hu Nai-bo, Zhang Hong-li, Qu Shi-qiang, Zhang Yue, Xiao Zhi-jian
Abstract excerpt
OBJECTIVE: To investigate the association of single nucleus polymorphisms(SNP)of tumor necrosis factor alpha (TNF-α) gene (-308 G>A and -238 G>A genotypes) with susceptibility to primary myelodysplastic syndromes (MDS). METHODS: Two SNPs (TNF-α-308 G>A,TNF-α-238 G>A) of TNF-α gene were detected by Taqman probes in 341 MDS patients and 365 unrelated-healthy controls. RESULTS: Compared to healthy controls, the...
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