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Article

Polymorphisms of IL-10 affect the severity and prognosis of myelodysplastic syndrome.

European journal of haematology - 1 Mar 2016

Kasamatsu Tetsuhiro, Saitoh Takayuki, Minato Yusuke, Shimizu Hiroaki, Yokohama Akihiko, Tsukamoto Norifumi, Handa Hiroshi, Sakura Toru, Murakami Hirokazu

Abstract excerpt

Polymorphisms of the interleukin-10 (IL-10) gene, which alter the production of IL-10, have been implicated in many cancers. We investigated the association between gene polymorphisms of the promoter region of IL-10 (-1082 G/A, IL-10-819 C/T, and -592 C/A) and the risk to develop myelodysplastic syndrome (MDS) and clinical features of MDS. Genomic DNA was extracted from 119 patients with MDS or chronic...

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Identifiers

PMID: 25941112
DOI: 10.1111/ejh.12577

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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