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Article

Polymorphisms in TGFbeta and TNFalpha are associated with the myelodysplastic syndrome phenotype.

Archives of pathology & laboratory medicine - 1 Dec 2007

Powers Martin P, Nishino Ha, Luo Yamin, Raza Alina, Vanguri Amulya, Rice Lawrence, Zu Youli, Chang Chung-Che Jeff

Abstract excerpt

CONTEXT: Myelodysplastic syndromes (MDSs) are characterized by ineffective hematopoiesis, excessive apoptosis, and the aberrant expression of a number of cytokines. The genes encoding these cytokines are significantly polymorphic. It is unknown whether these cytokine polymorphisms are associated with, and may therefore be playing a role in the pathogenesis of, MDS. OBJECTIVE: To determine if certain polymorphisms...

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Source

Identifiers

PMID: 18081437
DOI: 10.5858/2007-131-1789-PITATA

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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