Article
Common low-penetrance risk variants associated with breast cancer in Polish women.
BMC cancer - 30 Oct 2013
Ledwoń Joanna K, Hennig Ewa E, Maryan Natalia, Goryca Krzysztof, Nowakowska Dorota, Niwińska Anna, Ostrowski Jerzy
Abstract excerpt
BACKGROUND: Breast cancer is the most common type of cancer and the second leading cause of cancer-death among women in Poland. The known high-risk mutations account for 25% of familial aggregation cases and 5% of total breast cancer predisposition. Genome-wide association studies have identified a number of common low-penetrance genetic variants, but their contribution to disease risk differs between...
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