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Association of common genetic variants with breast cancer risk and clinicopathological characteristics in a Chinese population.

Breast cancer research and treatment - 1 Nov 2012

Chan M, Ji S M, Liaw C S, Yap Y S, Law H Y, Yoon C S, Wong C Y, Yong W S, Wong N S, Ng R, Ong K W, Madhukumar P, Oey C L, Tan P H, Li H H, Ang P, Ho G H, Lee A S G

Abstract excerpt

Genome-wide association studies (GWAS) have identified various genetic susceptibility loci for breast cancer based mainly on European-ancestry populations. Differing linkage disequilibrium patterns exist between European and Asian populations, and thus GWAS-identified single nucleotide polymorphisms (SNPs) in one population may not be of significance in another population. In order to explore the role of breast...

Topics

Adult
Alleles
Breast Neoplasms
China
Female
Genetic Association Studies
Genetic Loci
Genetic Predisposition to Disease
Humans
Linkage Disequilibrium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Receptors, Estrogen

Receptors, Progesterone

Risk Factors

Source

Identifiers

PMID: 22965832
DOI: 10.1007/s10549-012-2234-y

Genes

FGFR2
MRPS30
TLR1
TLR6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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