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Article

A mutation of the Col2a1 gene (G1170S) alters the transgenic murine phenotype and cartilage matrix homeostasis.

Journal of the Formosan Medical Association = Taiwan yi zhi - 1 Nov 2014

Yang Ruei-Cheng, Chen Ming-Hong, Chen Pei-Yu, Chen Ching-Yun, Tsai Shih-Feng, Cheng Cheng-Kung, Sun Jui-Sheng

Abstract excerpt

BACKGROUND/PURPOSE: Genomic studies have revealed that there is a significant association between a point mutation of the human Col2A1 gene (G1170S) and several hip disorders. The purpose of the study was to explore the phenotype and altered cartilage matrix homeostasis of transgenic mice carrying this mutated Col2a1 gene. METHODS: Wild-type and transgenic mice were used as the control and study groups,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24168833
DOI: 10.1016/j.jfma.2013.09.015

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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