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Growth retardation in transgenic mice harboring a type II collagen mutation.

Annals of the New York Academy of Sciences - 8 Jun 1996

Savontaus M, Vuorio E, Metsäranta M

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Topics

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Bone Development
Collagen
Growth Disorders
Growth Plate
Heterozygote
Homozygote
Mice, Transgenic

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PMID: 8702170
DOI: 10.1111/j.1749-6632.1996.tb56299.x

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Growth retardation in transgenic mice harboring a type II collagen mutation.PMID 8702170Read ↗

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Retarded skeletal development in transgenic mice with a type II collagen mutation.Semantic proximity Read ↗

An inbred line of transgenic mice expressing an internally deleted gene for type II procollagen (COL2A1). Young mice have a variable phenotype of a chondrodysplasia and older mice have osteoarthritic changes in joints.Semantic proximity Read ↗

Mechanisms of aberrant organization of growth plates in conditional transgenic mouse model of spondyloepiphyseal dysplasia associated with the R992C substitution in collagen II.Semantic proximity Read ↗

Type II collagen pro-alpha-chains containing a Gly574Ser mutation are not incorporated into the cartilage matrix of transgenic mice.Semantic proximity Read ↗

Transgenic mouse models for growth factor studies.Semantic proximity Read ↗

Abnormal craniofacial morphology and cartilage structure in transgenic mice harboring a Gly --> Cys mutation in the cartilage-specific type II collagen gene.Semantic proximity Read ↗

Depletion of cartilage collagen fibrils in mice carrying a dominant negative Col2a1 transgene affects chondrocyte differentiationSemantic proximity Read ↗

Transgenic mouse models in studies of skeletal disorders.Semantic proximity Read ↗

Abnormal craniofacial development and expression patterns of extracellular matrix components in transgenic Del1 mice harboring a deletion mutation in the type II collagen gene.Semantic proximity Read ↗

Rapid screening of transgenic type II and type XI collagen knock-out mice with three-primer PCR.Semantic proximity Read ↗

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