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Article

Generation and use of transgenic mice as models of osteoarthritis.

Methods in molecular medicine - 1 Jan 2004

Säämänen Anna-Marja, Vuorio Eero

Abstract excerpt

The term osteoarthritis (OA) represents a group of diseases characterized by gradual degradation of articular cartilage and a number of associated degenerative processes within the joint. Consequently, no single animal model is likely to fulfil all the criteria of OA. The present chapter discusses the possibilities of using transgenic technologies for modification of the mouse genome to generate animal models of...

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PMID: 15299207
DOI: 10.1385/1-59259-821-8:001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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