Article
Effect of pro-inflammatory cytokine (IFN-γ +874, IL-18-137 G/C,-607 C/A) genes in relation to risk of vesico-ureteral reflux.
Renal failure - 1 Feb 2014
Sadeghi-Bojd Simin, Kordi-Tamandani Dor Mohammad, Hashemi Mohammad
Abstract excerpt
AIM: The aim this work is to estimate whether genetic polymorphisms of +874 of IFN-γ and -137 G/C,-607 C/A of IL-18 genes are implicated in the development of VUR, because a vast literature indicates that genetic variations play a significant role in the pathogenesis of VUR. MATERIALS AND METHODS: The PCR single specific primer (SSP) and amplification refractory mutation system (ARMS) were applied for analyzing...
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