Article
Polymorphisms in genes coding for mediators in the interleukin cascade and their effect on susceptibility to sarcoidosis in the Slovenian population.
International journal of molecular medicine - 1 Sept 2007
Maver Ales, Medica Igor, Salobir Barbara, Sabovic Miso, Tercelj Marjeta, Peterlin Borut
Abstract excerpt
Sarcoidosis is a chronic inflammatory disease characterised by granulomatous inflammation in various organs. As genetic factors have been implicated in its aetiology, in our study we investigated whether the promotor polymorphisms in three genes coding for inflammatory mediators interleukin-6 (IL-6), interleukin-12 (IL-12), and interleukin-18 (IL-18) could be associated with susceptibility to sarcoidosis. The...
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