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Article

Interleukin-18 gene polymorphisms in tunisian patients with inflammatory bowel disease.

Digestion - 1 Jan 2011

Ben Aleya Walid, Sfar Imen, Habibi Imen, Mouelhi Leila, Aouadi Houda, Makhlouf Mouna, Ayed-Jendoubi Salwa, Najjar Taoufik, Ben Abdallah Taeib, Ayed Khaled, Gorgi Yousr

Abstract excerpt

AIM: Interleukin (IL)-18 can regulate the Th2-mediated immune response and it may be involved in the pathogenesis of Th1 and Th2 chronic inflammatory diseases. This study sought to detect a possible association between two single nucleotide polymorphisms (SNPs) (-137G/C and -607C/A) in the IL-18 gene promoter region and susceptibility to inflammatory bowel disease (IBD) including Crohn's disease (CD) and...

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Identifiers

PMID: 21273776
DOI: 10.1159/000319755

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