Article
Essential roles of Crk and CrkL in fibroblast structure and motility.
Oncogene - 23 Oct 2014
Park T-J, Curran T
Abstract excerpt
Cytosolic proteins containing SH2 and SH3 domains, such as Crk and Crk-like (CrkL), are broadly expressed adapters that interact with a variety of proteins to fulfill key roles in signal transduction pathways triggered by activation of receptor and non-receptor tyrosine kinases. Crk and CrkL are similar to each other in structure and biochemical function, although they provide both distinct, as well as...
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