Article
CpG island methylator phenotype and its relationship with prognosis in adult acute leukemia patients.
Hematology (Amsterdam, Netherlands) - 1 Sept 2014
Fu Hai-Ying, Wu Dan-Sen, Zhou Hua-Rong, Shen Jian-Zhen
Abstract excerpt
OBJECTIVE: To investigated the relationship between CpG island methylator phenotype (CIMP) and prognosis in adults with acute leukemia. METHODS: Bone marrow samples from 53 acute myeloid leukemia and 50 acute lymphoblastic leukemia patients were collected. The methylation status of 18 tumor suppressor genes was determined using methylation-specific polymerase chain reaction. RESULTS: Greater than 30% of acute...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
