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Article

Promoter DNA methylation pattern identifies prognostic subgroups in childhood T-cell acute lymphoblastic leukemia.

PloS one - 1 Jan 2013

Borssén Magnus, Palmqvist Lars, Karrman Kristina, Abrahamsson Jonas, Behrendtz Mikael, Heldrup Jesper, Forestier Erik, Roos Göran, Degerman Sofie

Abstract excerpt

BACKGROUND: Treatment of pediatric T-cell acute lymphoblastic leukemia (T-ALL) has improved, but there is a considerable fraction of patients experiencing a poor outcome. There is a need for better prognostic markers and aberrant DNA methylation is a candidate in other malignancies, but its potential prognostic significance in T-ALL is hitherto undecided. DESIGN AND METHODS: Genome wide promoter DNA methylation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Leukemic

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Identifiers

PMID: 23762353
DOI: 10.1371/journal.pone.0065373
PMCID: PMC3675104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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