Article
Replication of the association between a chromosome 9p21 polymorphism and coronary artery disease in Japanese and Korean populations.
Journal of human genetics - 1 Jan 2008
Hinohara Kunihiko, Nakajima Toshiaki, Takahashi Megumi, Hohda Shigeru, Sasaoka Taishi, Nakahara Ken-Ichi, Chida Kouji, Sawabe Motoji, Arimura Takuro, Sato Akinori, Lee Bok-Soo, Ban Ji-Min, Yasunami Michio, Park Jeong-Euy, Izumi Toru, Kimura Akinori
Abstract excerpt
Coronary artery disease (CAD) has become a major health problem in many countries. Recent genome-wide association studies have identified the association between rs1333049 on chromosome 9p21 and susceptibility to CAD in Caucasoid populations. In this study, we evaluated the associations of rs1333049 with CAD in Japanese (604 patients and 1,151 controls) and Koreans (679 patients and 706 controls). We found a...
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