A common variant on chromosome 4q25 is associated with prolonged PR interval in subjects with and without atrial fibrillation.

doi:10.1016/j.amjcard.2013.08.045

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Article

A common variant on chromosome 4q25 is associated with prolonged PR interval in subjects with and without atrial fibrillation.

The American journal of cardiology - 15 Jan 2014

Kolek Matthew J, Parvez Babar, Muhammad Raafia, Shoemaker M Benjamin, Blair Marcia A, Stubblefield Tanya, Kucera Gayle A, Denny Joshua C, Roden Dan M, Darbar Dawood

Abstract excerpt

Single nucleotide polymorphisms (SNPs) at chromosome 4q25 (near PITX2) are strongly associated with atrial fibrillation (AF). We assessed whether a 4q25-tagging SNP (rs2200733) is associated with PR interval duration in patients with lone and typical AF and controls. Patients with lone (n = 169) and typical (n = 269) AF enrolled in the Vanderbilt AF registry and controls (n = 1,403) derived from the Vanderbilt...

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PMID: 24161141
DOI: 10.1016/j.amjcard.2013.08.045
PMCID: PMC3947341

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PITX2

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