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Article

Significant Association Between CAV1 Variant rs3807989 on 7p31 and Atrial Fibrillation in a Chinese Han Population.

Journal of the American Heart Association - 7 May 2015

Chen Shanshan, Wang Chuchu, Wang Xiaojing, Xu Chengqi, Wu Manman, Wang Pengxia, Tu Xin, Wang Qing K

Abstract excerpt

BACKGROUND: Recent genome-wide association studies (GWAS) in European ancestry populations revealed several genomic loci for atrial fibrillation (AF). We previously replicated the 4q25 locus (PITX2) and 16q22 locus (ZFHX3) in the Chinese population, but not the KCNN3 locus on 1q21. With single-nucleotide polymorphism rs3807989 in CAV1 encoding caveolin-1, however, controversial results were reported in 2 Chinese...

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Source

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Identifiers

PMID: 25953654
DOI: 10.1161/JAHA.115.001980
PMCID: PMC4599427

Genes

CAV1
HCN4
KCNH2
KCNN3
PITX2
PRRX1
ZFHX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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