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Article

Genetic loci on chromosomes 4q25, 7p31, and 12p12 are associated with onset of lone atrial fibrillation before the age of 40 years.

The Canadian journal of cardiology - 1 Jan 2000

Olesen Morten S, Holst Anders G, Jabbari Javad, Nielsen Jonas B, Christophersen Ingrid E, Sajadieh Ahmad, Haunsø Stig, Svendsen Jesper H

Abstract excerpt

BACKGROUND: Three distinct genetic loci on chromosomes 1q21, 4q25, and 16q22 have been associated with atrial fibrillation (AF) in genome-wide association studies (GWAS). Five additional loci have been associated primarily with the PR interval and subsequently with AF. We aimed to investigate if 8 single nucleotide polymorphisms (SNPs), representing the 8 genomic loci previously linked with AF in genome-wide...

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Identifiers

PMID: 22336519
DOI: 10.1016/j.cjca.2011.11.016

Genes

CAV1
PITX2
SOX5

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Genetic loci on chromosomes 4q25, 7p31, and 12p12 are associated with onset of lone atrial fibrillation before the age of 40 years.PMID 22336519Read ↗

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