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Article

Dense Deposit Disease and C3 Glomerulopathy

23 Oct 2013

Abstract excerpt

C3 glomerulopathy refers to those renal lesions characterized histologically by predominant C3 accumulation within the glomerulus, and pathogenetically by aberrant regulation of the alternative pathway of complement. Dense deposit disease is distinguished from other forms of C3 glomerulopathy by its characteristic appearance on electron microscopy. The extent to which dense deposit disease also differs from other...

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PMID: 24161036
DOI: 10.1016/j.semnephrol.2013.08.002

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