Article
Clinicopathological features of C3 glomerulopathy in children: a single-center experience.
Pediatric nephrology (Berlin, Germany) - 1 Jan 2020
Drake Keri A, Ellington Natalie, Gattineni Jyothsna, Torrealba Jose R, Hendricks Allen R
Abstract excerpt
BACKGROUND: C3 glomerulopathy (C3G) is defined by dominant glomerular deposition of C3 and minimal or no immunoglobulin, with two subtypes-dense deposit disease (DDD) and C3 glomerulonephritis (C3GN)-distinguished by features on electron microscopy (EM). Given that this rare disease has generally unfavorable yet highly variable outcomes, we sought out to review the histopathology, complement/genetic studies, and...
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