Article
Complement inhibition in C3 glomerulopathy.
Seminars in immunology - 1 Jun 2016
Nester Carla M, Smith Richard J H
Abstract excerpt
C3 glomerulopathy (C3G) describes a spectrum of glomerular diseases defined by shared renal biopsy pathology: a predominance of C3 deposition on immunofluorescence with electron microscopy permitting disease sub-classification. Complement dysregulation underlies the observed pathology, a causal relationship that is supported by well described studies of genetic and acquired drivers of disease. In this article, we...
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