Article
Three polymorphisms in promoter of protein C gene with endothelial protein c receptor gene and risk of venous thrombosis.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Dec 2013
Horakova Kristyna, Kolorz Michal, Bartosova Ladislava, Pechacek Vaclav, Wroblova Katerina
Abstract excerpt
The primary abnormalities that are associated with a risk of venous thrombosis are the deficiencies of protein C. Protein C (PROC), encoded by the PROC gene, acts through its affinity for binding to its transmembrane endothelial cell protein C receptor (EPCR) encoded by the EPCR gene. The objective of the study was to analyze the link between three polymorphisms in the promoter of PROC gene, the polymorphism in...
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