Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Compound heterozygous protein C deficiency with pulmonary embolism caused by a novel PROC gene mutation: Case report and literature review.

Medicine - 21 Oct 2022

Zhang Zhaorui, Yang Zhen, Chen Mei, Li Yuzhu

Abstract excerpt

RATIONALE: Protein C is an anticoagulation agent, and protein C deficiency results in vascular thrombosis disease. Hereditary protein C deficiency is a risk factor for pulmonary embolism in adults. Pathogenic variants of the Protein C, Inactivator Of Coagulation Factors Va And VIIIa (PROC) gene which encodes protein C have been identified as a cause of protein C deficiency. PATIENT CONCERNS: We describe a patient...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anticoagulants
Share to Blood Coagulation Factors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Protein C

Share to Protein C Deficiency

Share to Pulmonary Embolism

Share to Thrombosis

Source

Open in PubMed Open full text

Identifiers

PMID: 36281079
DOI: 10.1097/MD.0000000000031221
PMCID: PMC9592271

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Compound heterozygous protein C deficiency with pulmonary embolism caused by a novel PROC gene mutation: Case report and literature review.PMID 36281079Read ↗

Antithrombin deficiency and decreased protein C activity in a young man with venous thromboembolism: a case report.Semantic proximity Read ↗

Analysis of Four Hereditary Protein C Deficiencies Associated with Vascular ThromboembolismSemantic proximity Read ↗

Analysis of four hereditary protein C deficiencies associated with vascular thromboembolism.Semantic proximity Read ↗

Clinical and genetic features of protein C deficiency in 23 unrelated Chinese patients.Semantic proximity Read ↗

[Clinical phenotype and gene mutation analysis of 12 patients with hereditary protein C deficiency in different families].Semantic proximity Read ↗

Two novel compound heterozygous mutations associated with types I and II protein C deficiency with unusual phenotypes.Semantic proximity Read ↗

A novel silent substitution (C8516T) in exon 9 of the human PROC gene.Semantic proximity Read ↗

A Series of 14 Polish Patients with Thrombotic Events and PC Deficiency-Novel c.401-1G>A PROC Gene Splice Site Mutation in a Patient with AneurysmsSemantic proximity Read ↗

Novel insights into inherited protein C deficiency from an interactive PROC variant database.Semantic proximity Read ↗

Genetic background analysis of protein C deficiency demonstrates a recurrent mutation associated with venous thrombosis in Chinese population.Semantic proximity Read ↗

The clinical presentation and genotype of protein C deficiency with double mutations of the protein C gene.Semantic proximity Read ↗

Molecular characterization of novel splice site mutation causing protein C deficiency.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.