Article
Soluble endothelial protein C receptor (sEPCR) levels and venous thromboembolism in carriers of two dysfunctional protein C variants.
Thrombosis research - 1 Jan 2006
Simioni Paolo, Morboeuf Olivier, Tognin Giulio, Gavasso Sabrina, Tormene Daniela, Woodhams Barry, Pagnan Antonio
Abstract excerpt
The role of the A3 haplotype and soluble endothelial protein C receptor (sEPCR) plasma levels in predisposing the carriers of two peculiar dysfunctional protein C (PC) variants (PC Arg-1-->Cys and PC Arg-1-->Leu, also known as PC Padua(2) and PC Padua(3), respectively) to venous thromboembolism (VTE) has been evaluated. The levels of sEPCR have been assessed in family members during 6 years of follow-up and...
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