Article
The H1 haplotype of the endothelial protein C receptor protects against arterial thrombosis in patients with antiphospholipid syndrome.
Thrombosis research - 1 Sept 2018
Plasín-Rodríguez Miguel Angel, Rodríguez-Pintó Ignasi, Patricio Patricia, Monteagudo Joan, Cervera Ricard, Reverter Joan Carles, Espinosa Gerard, Tàssies Dolors
Abstract excerpt
INTRODUCTION: Genetic variants in the endothelial protein C receptor gene (PROCR) may contribute to the thrombosis risk by regulating levels of the soluble form of this protein (sEPCR). We evaluated whether PROCR polymorphisms and sEPCR levels play a role in the thrombotic manifestations of antiphospholipid syndrome. MATERIALS AND METHODS: One hundred and seventy-five patients (62 with primary antiphospholipid...
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