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Article

Chromosomal aberrations in primary PDGFRA-mutated gastrointestinal stromal tumors.

Human pathology - 1 Jan 2014

Schaefer Inga-Marie, Delfs Christian, Cameron Silke, Gunawan Bastian, Agaimy Abbas, Ghadimi B Michael, Haller Florian

Abstract excerpt

Approximately 15% of gastrointestinal stromal tumors (GISTs) harbor mutations in the platelet-derived growth factor receptor α (PDGFRA) gene. Chromosomal aberrations play a crucial role in tumor progression and correlate with clinical behavior. Imbalances, particularly in PDGFRA-mutated GISTs, ha...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptor, Platelet-Derived Growth Factor alpha

Source

Identifiers

PMID: 24157063
DOI: 10.1016/j.humpath.2013.05.027

Genes

PDGFRA
KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24157063-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Chromosomal aberrations in primary PDGFRA-mutated gastrointestinal stromal tumors.PMID 24157063Read ↗

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