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Article

Anaplastic lymphoma kinase expression in PDGFRA-mutated gastrointestinal stromal tumors probably correlates with poor prognosis.

World journal of surgical oncology - 29 Apr 2023

Wu Ying, Gao Beibei, Xia Qin, Zhu Yili, Wang Na, Chang Xiaona, Huang Bo, Luo Danju, Zhang Jiwei, Zhang Peng, Shi Heshui, Fan Jun, Nie Xiu

Abstract excerpt

BACKGROUND: Anaplastic lymphoma kinase (ALK) overexpression and gene alterations have been detected in several mesenchymal tumors, with significant implications for diagnosis, therapy and prognosis. However, few studies have investigated the correlation between ALK expression status and clinicopathological characteristics in patients with gastrointestinal stromal tumors (GISTs). METHODS: A total of 506 GIST...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37120571
DOI: 10.1186/s12957-023-03019-4
PMCID: PMC10148552

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