Article
Results on prognostic value of mutations in localized gastrointestinal stromal tumors (GIST) in one single center.
Revista espanola de enfermedades digestivas - 1 Aug 2012
Garcés-Albir Marina, Marti-Obiol Roberto, López-Mozos Fernando, Calabuig-Fariñas Silvia, Navarro-Ros Samuel, Ortega-Serrano Joaquín
Abstract excerpt
INTRODUCTION: to study the prognostic value of mutations in KIT or PDGFRA in gastrointestinal stromal tumors (GIST) managed in our department. MATERIALS AND METHODS: forty five patients with localized GIST underwent surgery between 1998 and 2010. Thirty six patients were enrolled in a retrospective study. DNA was isolated from 3 to 5 ìm sections of fixed and paraffin-embedded tissue. Exon 9, 11, 13 and 17 of...
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