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Article

Multiple Hodgkin lymphoma-associated loci within the HLA region at chromosome 6p21.3.

Blood - 21 Jul 2011

Moutsianas Loukas, Enciso-Mora Victor, Ma Yussanne P, Leslie Stephen, Dilthey Alexander, Broderick Peter, Sherborne Amy, Cooke Rosie, Ashworth Alan, Swerdlow Anthony J, McVean Gilean, Houlston Richard S

Abstract excerpt

Since an association between the human leukocyte antigen (HLA) region and Hodgkin lymphoma (HL) was first reported in 1967, many studies have reported associations between HL risk and both single nucleotide polymorphism (SNP) and classic HLA allele variation in the major histocompatibility complex. However, population stratification and the extent and complexity of linkage disequilibrium within the major...

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PMID: 21596858
DOI: 10.1182/blood-2011-03-339630

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