Article
ATHENA: the analysis tool for heritable and environmental network associations.
Bioinformatics (Oxford, England) - 1 Mar 2014
Holzinger Emily R, Dudek Scott M, Frase Alex T, Pendergrass Sarah A, Ritchie Marylyn D
Abstract excerpt
MOTIVATION: Advancements in high-throughput technology have allowed researchers to examine the genetic etiology of complex human traits in a robust fashion. Although genome-wide association studies have identified many novel variants associated with hundreds of traits, a large proportion of the estimated trait heritability remains unexplained. One hypothesis is that the commonly used statistical techniques and...
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