Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Requirement of estrogen receptor alpha DNA-binding domain for HPV oncogene-induced cervical carcinogenesis in mice

22 Oct 2013

Abstract excerpt

Cervical cancer is caused by human papillomavirus (HPV) in collaboration with other non-viral factors. The uterine cervix is hormone responsive and female hormones have been implicated in the pathogenesis of the disease. HPV transgenic mice expressing HPV16 oncogenes E6 (K14E6) and/or E7 (K14E7) have been employed to study a mechanism of estrogen and estrogen receptor α (ERα) in cervical carcinogenesis. A chronic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cervical Cancer and HPV Research
Share to Endometrial and Cervical Cancer Treatments
Share to Estrogen and related hormone effects

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24148821
DOI: 10.1093/carcin/bgt350

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Requirement of estrogen receptor alpha DNA-binding domain for HPV oncogene-induced cervical carcinogenesis in micePMID 24148821Read ↗

Requirement for Estrogen Receptor α in a Mouse Model for Human Papillomavirus–Associated Cervical CancerSemantic proximity Read ↗

Molecular Signature of HPV-Induced Carcinogenesis: pRb, p53 and Gene Expression ProfilingSemantic proximity Read ↗

Critical roles for non-pRb targets of human papillomavirus type 16 E7 in cervical carcinogenesis.Semantic proximity Read ↗

Estrogen contributes to the onset, persistence, and malignant progression of cervical cancer in a human papillomavirus-transgenic mouse model.Semantic proximity Read ↗

The Human Papillomavirus E6 Oncogene Dysregulates the Cell Cycle and Contributes to Cervical Carcinogenesis through Two Independent ActivitiesSemantic proximity Read ↗

Requirement of epidermal growth factor receptor for hyperplasia induced by E5, a high-risk human papillomavirus oncogene.Semantic proximity Read ↗

Chronic estrogen-induced cervical and vaginal squamous carcinogenesis in human papillomavirus type 16 transgenic mice.Semantic proximity Read ↗

A Role for HPV16 E5 in Cervical CarcinogenesisSemantic proximity Read ↗

Beta-catenin accelerates human papilloma virus type-16 mediated cervical carcinogenesis in transgenic mice.Semantic proximity Read ↗

ERa-36 instead of ERa mediates the stimulatory effects of estrogen on the expression of viral oncogenes HPV E6/E7 and the malignant phenotypes in cervical cancer cells.Semantic proximity Read ↗

E6-Associated Protein Is Required for Human Papillomavirus Type 16 E6 to Cause Cervical Cancer in MiceSemantic proximity Read ↗

Estrogen induces genomic instability in high-risk HPV-infected cervix and promotes the carcinogenesis of cervical adenocarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.