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Article

A Role for HPV16 E5 in Cervical Carcinogenesis

24 Mar 2010

Abstract excerpt

A subset of the mucosotropic human papillomaviruses (HPV), including HPV16, are etiologic agents for the vast majority of cervical cancers, other anogenital cancers, and a subset of head and neck squamous cell carcinomas. HPV16 encodes three oncogenes: E5, E6, and E7. Although E6 and E7 have been well-studied and clearly shown to be important contributors to these cancers, less is known about E5. In this study,...

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PMID: 20332225
DOI: 10.1158/0008-5472.can-09-3436

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