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E6-Associated Protein Is Required for Human Papillomavirus Type 16 E6 to Cause Cervical Cancer in Mice

8 Jun 2010

Abstract excerpt

High-risk human papillomaviruses (HPV) cause certain anogenital and head and neck cancers. E6, one of three potent HPV oncogenes that contribute to the development of these malignancies, is a multifunctional protein with many biochemical activities. Among these activities are its ability to bind and inactivate the cellular tumor suppressor p53, induce expression of telomerase, and bind to various other proteins,...

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PMID: 20530688
DOI: 10.1158/0008-5472.can-09-3307

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E6-Associated Protein Is Required for Human Papillomavirus Type 16 E6 to Cause Cervical Cancer in MicePMID 20530688Read ↗

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