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Article

Maturation and application of phenome-wide association studies.

Trends in genetics : TIG - 1 Apr 2022

Liu Shiying, Crawford Dana C

Abstract excerpt

In the past 10 years since its introduction, phenome-wide association studies (PheWAS) have uncovered novel genotype-phenotype relationships. Along the way, PheWAS have evolved in many aspects as a study design with the expanded availability of large data repositories with genome-wide data linked to detailed phenotypic data. Advancement in methods, including algorithms, software, and publicly available integrated...

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Identifiers

PMID: 34991903
DOI: 10.1016/j.tig.2021.12.002
PMCID: PMC8930498

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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