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Article

Female-specific effects of the catechol-O-methyl transferase Val158Met gene polymorphism on working memory-related brain function.

Aging - 22 Nov 2020

Fan Jialing, Yang Caishui, Liu Zhen, Li He, Han Yan, Chen Kewei, Chen Chuansheng, Wang Jun, Zhang Zhanjun

Abstract excerpt

The catechol-O-methyltransferase (COMT) Val158Met polymorphism has been associated with working memory (WM) in many studies, but the results have not been consistent. One plausible explanation is sex-specific effects of this polymorphism as reported in several studies. The current study aimed to explore the sex-specific effects of the COMT Val158Met polymorphism on WM-related brain function in an elderly sample....

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Identifiers

PMID: 33221753
DOI: 10.18632/aging.104059
PMCID: PMC7762470

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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