Article
Sex-specific effects of NLRP6/AVR and ADM loci on susceptibility to essential hypertension in a Sardinian population.
PloS one - 1 Jan 2013
Glorioso Nicola, Herrera Victoria L, Didishvili Tamara, Ortu Maria F, Zaninello Roberta, Fresu Giovanni, Argiolas Guiseppe, Troffa Chiara, Ruiz-Opazo Nelson
Abstract excerpt
Coronary artery disease, heart failure, fatal arrhythmias, stroke, and renal disease are the most common causes of mortality for humans, and essential hypertension remains a major risk factor. Elucidation of susceptibility loci for essential hypertension has been difficult because of its complex, multifactorial nature involving genetic, environmental, and sex- and age-dependent nature. We investigated whether the...
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