Article
Lack of association of mirSNP rs11174811 in AVPR1A gene with arterial blood pressure and hypertension in South Indian population.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jan 2018
Koshy Linda, Vijayalekshmi S V, Harikrishnan S, Raman Kutty V, Jissa V T, Jayakumaran Nair A, Gangaprasad A, Nair G M, Sudhakaran P R
Abstract excerpt
Epigenetic regulation of arterial blood pressure mediated through mirSNPs in renin-angiotensin aldosterone system (RAAS) genes is a less explored hypothesis. Recently, the mirSNP rs11174811 in the 3'UTR of the AVPR1A gene was associated with higher arterial blood pressure in a large study population from the Study of Myocardial Infarctions Leiden (SMILE). The aim of the present study was to replicate the...
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