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Article

Microsatellites and SNPs linkage analysis in a Sardinian genetic isolate confirms several essential hypertension loci previously identified in different populations.

BMC medical genetics - 28 Aug 2009

Mocci Evelina, Concas Maria P, Fanciulli Manuela, Pirastu Nicola, Adamo Mauro, Cabras Valentina, Fraumene Cristina, Persico Ivana, Sassu Alessandro, Picciau Andrea, Prodi Dionigio A, Serra Donatella, Biino Ginevra, Pirastu Mario, Angius Andrea

Abstract excerpt

BACKGROUND: A multiplicity of study designs such as gene candidate analysis, genome wide search (GWS) and, recently, whole genome association studies have been employed for the identification of the genetic components of essential hypertension (EH). Several genome-wide linkage studies of EH and blood pressure-related phenotypes demonstrate that there is no single locus with a major effect while several genomic...

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PMID: 19715579
DOI: 10.1186/1471-2350-10-81
PMCID: PMC2741446

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