Article
Association of a BLVRA common polymorphism with essential hypertension and blood pressure in Kazaks.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jan 2011
Lin Rong, Wang Xiaofeng, Zhou Weichen, Fu Wenqing, Wang Ying, Huang Wei, Jin Li
Abstract excerpt
Biliverdin reductase A (BLVRA) is a powerful intracellular antioxidant enzyme and an antagonist to insulin-mediated glucose uptake by the cells. Increased oxidative stress and insulin-resistance (IR) are associated with increased risk for hypertension. Therefore, we hypothesized that BLVRA might be attributable to the variation of susceptibility to essential hypertension, and investigated single nucleotide...
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