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Article

Association of ATP1A1 and dear single-nucleotide polymorphism haplotypes with essential hypertension: sex-specific and haplotype-specific effects.

Circulation research - 25 May 2007

Glorioso Nicola, Herrera Victoria L M, Bagamasbad Pia, Filigheddu Fabiana, Troffa Chiara, Argiolas Giuseppe, Bulla Emanuela, Decano Julius L, Ruiz-Opazo Nelson

Abstract excerpt

Essential hypertension remains a major risk factor for cardiovascular and cerebrovascular diseases. As a complex multifactorial disease, elucidation of susceptibility loci remains elusive. ATP1A1 and Dear are candidate genes for 2 closely linked rat chromosome-2 blood pressure quantitative trait loci. Because corresponding human syntenic regions are on different chromosomes, investigation of ATP1A1 (chromosome...

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PMID: 17446437
DOI: 10.1161/01.RES.0000267716.96196.60

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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