Article
Drosophila Dyrk2 plays a role in the development of the visual system.
PloS one - 1 Jan 2013
Luebbering Nathan, Charlton-Perkins Mark, Kumar Justin P, Lochead Pamela A, Rollmann Stephanie M, Cook Tiffany, Cleghon Vaughn
Abstract excerpt
The DYRKs (dual-specificity tyrosine phosphorylation-regulated kinases) are a conserved family of protein kinases that are associated with a number of neurological disorders, but whose biological targets are poorly understood. Drosophila encodes three Dyrks: minibrain/Dyrk1A, DmDyrk2, and DmDyrk3. Here we describe the creation and characterization of a DmDyrk2 null allele, DmDyrk2(1w17) . We provide evidence that...
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