Article
G protein-coupled receptor transactivation: from molecules to mice.
Methods in cell biology - 1 Jan 2013
Jonas Kim C, Rivero-Müller Adolfo, Huhtaniemi Ilpo T, Hanyaloglu Aylin C
Abstract excerpt
G protein-coupled receptors (GPCRs) mediate a diverse range of physiological functions via activation of complex signaling systems. Organization of GPCRs in to dimers and oligomers provides a mechanism for both signal diversity and specificity in cellular responses, yet our understanding of the physiological significance of dimerization, particularly homodimerization, has not been forthcoming. This chapter will...
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