G protein-coupled receptor transactivation: from molecules to mice.

doi:10.1016/B978-0-12-408143-7.00023-2

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Article

G protein-coupled receptor transactivation: from molecules to mice.

Methods in cell biology - 1 Jan 2013

Jonas Kim C, Rivero-Müller Adolfo, Huhtaniemi Ilpo T, Hanyaloglu Aylin C

Abstract excerpt

G protein-coupled receptors (GPCRs) mediate a diverse range of physiological functions via activation of complex signaling systems. Organization of GPCRs in to dimers and oligomers provides a mechanism for both signal diversity and specificity in cellular responses, yet our understanding of the physiological significance of dimerization, particularly homodimerization, has not been forthcoming. This chapter will...

Topics

Animals
Chromosomes, Artificial, Bacterial
Embryo, Mammalian
Female
Fertility
Fluorescent Antibody Technique
Genes, Reporter
HEK293 Cells
Humans
Luciferases
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Mice, Transgenic

Mutation

Protein Binding

Protein Isoforms

Protein Multimerization

Receptors, LH

Source

Open in PubMed

Identifiers

PMID: 24143991
DOI: 10.1016/B978-0-12-408143-7.00023-2

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