Multiple signaling states of G-protein-coupled receptors.

doi:10.1124/pr.57.2.2

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Multiple signaling states of G-protein-coupled receptors.

Pharmacological reviews - 1 Jun 2005

Perez Dianne M, Karnik Sadashiva S

Abstract excerpt

Studies have been amassed in the past several years indicating that an agonist can conform a receptor into an activation state that is dependent upon an intrinsic property of the agonist usually based upon its chemical composition. Theoretically, each different agonist could impart its own unique activation state. Evidence for multiple signaling states for the G-protein-coupled receptors will be reviewed and is...

Topics

Animals
Humans
Models, Molecular
Mutation
Protein Binding
Protein Conformation
Receptors, G-Protein-Coupled
Rhodopsin
Signal Transduction

Source

Open in PubMed

Identifiers

PMID: 15914464
DOI: 10.1124/pr.57.2.2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics